Cervical Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Cervical Cancer, including details on symptoms, vaccine, screening, treatment, human papilloma virus (hpv), information.

Phase II study on weekly bolus topotecan in advanced or recurrent cervical cancer.

Lorusso D, Mainenti S, Pietragalla A, Fusco E, Malaguti P, Masciullo V, Scambia G

Department of Gynaecologic Oncology, Catholic University of the Sacred Heart, Largo Agostino Gemelli 8, Rome, Italy. kettalorusso@libero.it

Published 6 September 2011 in Oncology, 80(5): 390-4.
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Articles on Cervical Cancer published 30 August 2011:

A consensus-based guideline defining clinical target volume for primary disease in external beam radiotherapy for intact uterine cervical cancer.   Jpn J Clin Oncol, 41(9): 1119-26.

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Articles on Cervical Cancer published 29 August 2011:

Suppression of HPV E6 and E7 expression by BAF53 depletion in cervical cancer cells.   Biochem Biophys Res Commun, 412(2): 328-33.

Deregulation of the expression of human papillomavirus (HPV) oncogenes E6 and E7 plays a pivotal role in cervical carcinogenesis because the E6 and E7 proteins neutralize p53 and Rb tumor suppressor pathways, respectively. In approximately 90% of all cervical carcinomas, HPVs are found to be integrated into the host genome. Following integration, the core-enhancer element and P105 promoter that control expression of E6 and E7 adopt a chromatin structure that is different from that of episomal ... [Abstract] [Full-text]

Articles on Cervical Cancer published 23 August 2011:

Enhancer of zeste homolog 2 expression is associated with tumor cell proliferation and invasion in cervical cancer.   Am J Med Sci, 342(3): 198-204.

[Abstract] [Full-text]

Articles on Cervical Cancer published 22 August 2011:

Impact of post-therapy positron emission tomography on prognostic stratification and surveillance after chemoradiotherapy for cervical cancer.   Cancer, 117(17): 3981-8.

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Articles on Cervical Cancer published 18 August 2011:

MRI-based pre-planning in patients with cervical cancer treated with three-dimensional brachytherapy.   Br J Radiol, 84(1005): 850-6.

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Articles on Cervical Cancer published 16 August 2011:

Differential expression of Oct4 in HPV-positive and HPV-negative cervical cancer cells is not regulated by DNA methyltransferase 3A.   Tumour Biol, 32(5): 941-50.

The colony-forming ability of cervical cancer is affected by many factors. Oct4, an important transcription factor, is highly expressed in several tumors and promotes the colony-forming ability of cancer cells. Thus, it is considered a potential target for the treatment of cancer. However, we know little about the expression level of Oct4 and its epigenetic regulatory mechanism in cervical cancer cells. In this study, we are the first to observe that human papillomavirus (HPV)-positive cervical ... [Abstract] [Full-text]

Articles on Cervical Cancer published 15 August 2011:

Calibrating longitudinal models to cross-sectional data: the effect of temporal changes in health practices.   Value Health, 14(5): 700-4.

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Use of high-risk human papillomavirus testing in patients with low-grade squamous intraepithelial lesions.   Cancer Cytopathol, 119(4): 228-34.

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